CBD and Zoloft: What Happens When You Take Them Together?

Antidepressant is a psychiatric medication used to treat depression and anxiety. Some antidepressants are selective serotonin reuptake inhibitors (SSRIs), citalopram, fluoxetine, escitalopram, citalopram, paroxetine, sertraline.

According to a study by the University of Sao Paulo, taking citalopram (Celexa) with CBD will result in lower blood levels of citalopram than usual, thus requiring an increase of citalopram dosage.

Zoloft (sertraline) is an SSRI antidepressant. The citalopram study concluded that citalopram blood levels decreased when administered concomitantly with CBD, resulting in a reduced therapeutic effect of citalopram. It was found that SERT protein binding sites were affected by citalopram-CBD interactions, which may affect the pharmacokinetics of citalopram.

CBD and Zoloft are two treatments that can be used for anxiety. But what do they have in common? They both work with serotonin, a chemical in the brain responsible for moods and feelings of happiness or sadness. If you’re considering taking CBD oil to help your anxiety, it’s essential to know how CBD interacts with other medications like Zoloft before you make any decisions about treatment. Read on to find out more about CBD and Zoloft!

CBD & Zoloft

CBD and Zoloft both work to help relieve anxiety by altering serotonin levels in the brain. When CBD oil is taken with an SSRI, such as citalopram or sertraline (Zoloft), blood serum concentrations of citalopram may be decreased slightly. This might need a dosage adjustment for citalopram.

CBD is known to aid with anxiety by stimulating serotonin receptors in the brain, which may cause citalopram blood levels to drop when the two are combined.

What is CBD?

CBD is short for cannabidiol, one of the active cannabinoids identified in cannabis. It’s thought to be responsible for many of the effects associated with marijuana use, but without some of the side effects that THC causes.

CBD oil comes from hemp plants and can contain varying levels of THC—the main psychoactive compound found in cannabis—depending on the product. It’s sold as a tincture, capsule, oil and more, and is taken orally or added to food.

Learn more: Best CBD Oil Brand for Autism

What is Zoloft?

Zoloft, also known as citalopram or cipralex, is an antidepressant that works by blocking serotonin reuptake. SSRIs (selective serotonin reuptake inhibitors) are the most often prescribed antidepressants. They work by boosting serotonin levels in the brain, which can lead to benefits like reduced anxiety and enhanced mood.

Zoloft is taken orally, usually once a day, with or without food in the morning. It might take some time before you start to notice an improvement in your mood and how you feel, so it’s vital to give Zoloft at least four weeks of treatment before deciding whether or not it’s working for you. This medication may take up to two weeks before you start feeling better.

Can You Take CBD with Zoloft?

It’s not recommended to take citalopram with CBD because citalopram is an SSRI, which could alter the serotonin levels in your brain when taken together. This may reduce citalopram blood serum concentrations slightly and result in a reduced therapeutic effect of citalopram.

The same thing might happen if you’re taking citalopram with CBD. Citalopram blood serum concentrations may be decreased slightly, which could result in a reduced therapeutic effect of citalopram.

CBD may interfere with your body’s absorption of citalopram, so tell your doctor about any supplements you’re taking before starting Zoloft or citalopram treatment.

CBD isn’t likely to cause any harmful interactions with Zoloft, CBD, and citalopram; however, CBD can interact with other medications.

If you’re currently taking CBD oil or considering using CBD for anxiety treatment, CBD may interfere with the way your body absorbs and processes drugs like Zoloft (sertraline). This can cause CBD and Zoloft blood serum concentrations to drop slightly, meaning CBD won’t be as effective for treating your anxiety.

If you’re taking CBD oil along with SSRIs like citalopram or sertraline (Zoloft), it might affect how much of the medication gets into your bloodstream. This could require a dosage adjustment for CBD oil.

Can CBD Replace Zoloft?

CBD is sometimes used as an alternative treatment for depression and anxiety. It’s thought to help reduce stress by activating serotonin receptors in the brain, leading to citalopram blood levels decreasing when taken together.

Zoloft works on a different part of your body than CBD does, so they’re not equivalent treatments, but it might be worth trying CBD for yourself if you’re looking to replace Zoloft.

Suppose citalopram blood serum concentrations are decreased slightly. In that case, it could reduce the therapeutic effect of citalopram, so be sure to tell your doctor about all supplements, herbs, or medications you take before starting treatment with citalopram or any other antidepressants.

Citalopram blood serum concentrations may be slightly lowered, resulting in a reduced therapeutic effect of citalopram. Before starting citalopram treatment, tell your doctor about any supplements, herbs, or drugs you’re taking.

Learn more: Can CBD Help with Nerve Pain?

Final Thoughts on CBD and Zoloft

CBD and Zoloft are two medications that you should not take together. CBD is thought to reduce anxiety by activating serotonin receptors in the brain and lower citalopram blood serum concentrations when taken together. Hence, it’s important to tell your doctor about any supplements, herbs, or medication you’re taking before starting treatment with this type of antidepressant.

Zoloft is an SSRI antidepressant that works on a different part of your body than CBD does, so it’s not the same thing, but you may want to try taking CBD if citalopram isn’t working for you or you’re looking for replacement treatment. Be sure to tell your doctor about any supplements, herbs, or drugs you’re taking before starting treatment with citalopram.

We hope you’ve learned a lot about CBD oil and Zoloft, what you should know before taking them together, and that they’re not equivalent treatments. As always, be sure to follow instructions from your doctor when starting any new medication or supplement treatment.

So, what are your thoughts on CBD oil and Zoloft? Leave your comment below.

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